Hereditary Breast and Ovarian Cancer Syndrome—are you at risk? Should you be tested? Take this quiz to find out.
 
Breast and ovarian cancers are common cancers that affect women. But only some of them are hereditary. Hereditary cancer can happen when a parent passes on a mutation (change) in a BRCA1 or BRCA2 gene to a son or daughter. Changes in these 2 genes cause about 3% to 5% of all cancers in the breast and up to 15% of all cancers in the ovary. Changes in the 2 genes also increase the risk for breast and/or prostate cancer in men.
 
This quiz will help you find out if you might be at risk for these hereditary cancers. If you answer yes to any of these questions, talk with your doctor or genetic counselor about the BRCAvantage™ test. This test looks for mutations in the BRCA1 and BRCA2 genes. If your BRCAvantage test is positive, you are at high risk for hereditary cancer. If you are at high risk, there are steps you can take to decrease your risk.
 
Taking steps today can help keep you healthy tomorrow and in the years to come.
 
For Women

  1. Does at least 1 of your blood relatives have a BRCA1 or BRCA2 mutation?
  2. Have you had breast cancer at age 50 or younger?
  3. Have you had ovarian, fallopian tube, or peritoneal cancer?
  4. Have you had “triple negative” (ER/PR/HER2 negative) breast cancer at age 60 or younger?
  5. Are you an Ashkenazi Jew who has had breast cancer?
  6. Have you had breast cancer: a. And 1 or more close blood relative* with breast cancer at age 50 or younger? b. And 2 or more close blood relatives* with breast cancer at any age? c. And 1 or more close blood relative* with ovarian cancer? d. And 2 or more close blood relatives* with pancreatic or aggressive prostate cancer? e. And a close male blood relative with breast cancer?
  7. Have you had pancreatic cancer and 2 or more close blood relatives* with breast, ovarian, pancreatic, or aggressive prostate cancer?
  8. Do you have a family history of breast or ovarian cancer?: a. You have a family history if your mother, sister, daughter, grandmother, aunt, niece, or granddaughter can answer yes to any of the above questions in the Quiz for Women. b. You have a family history if your father, brother, son, grandfather, uncle, nephew, or grandson can answer yes to any of the questions in the Quiz for Men. c. You have a family history if your first cousin, great-grandparent, or great-grandchild had breast or ovarian cancer and 2 or more close blood relatives with breast cancer (at least one with breast cancer at age 50 or younger) and/or ovarian cancer.

For Men

  1. Does at least 1 of your blood relatives have a BRCA1 or BRCA2 mutation?
  2. Have you had breast cancer?
  3. Have you had pancreatic or aggressive prostate cancer and 2 or more close blood relatives with breast, ovarian, pancreatic, or aggressive prostate cancer?
  4. Do you have a family history of breast or ovarian cancer? a. You have a family history if your mother, sister, daughter, grandmother, aunt, niece, or granddaughter can answer yes to any question in the Quiz for Women. b.You have a family history if your father, brother, son, grandfather, uncle, nephew, or grandson can answer yes to any of the above questions in the Quiz for Men. c.You have a family history if your first cousin, great-grandparent, or great-grandchild had breast or ovarian cancer and 2 or more close blood relatives with breast cancer (at least one with breast cancer at age 50 or younger) and/or ovarian cancer.
     

* Close blood relatives include: first-degree relatives: mother, father, sister, brother, or child; second-degree relatives: grandparent, aunt, uncle, niece, nephew, grandchild on same side of the family; third-degree relatives: first cousin, great-grandparent, great-grandchildren on same side of the family.

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